node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCDG_00618 | HCDG_03319 | C6H1N6 | C6HAT8 | Serine/threonine protein kinase. | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.998 |
HCDG_00618 | HCDG_04616 | C6H1N6 | C6HF93 | Serine/threonine protein kinase. | Uncharacterized protein. | 0.645 |
HCDG_00618 | HCDG_05766 | C6H1N6 | C6HHT5 | Serine/threonine protein kinase. | RNA polymerase II transcription mediator complex subunit. | 0.998 |
HCDG_00618 | MED17 | C6H1N6 | C6H5I0 | Serine/threonine protein kinase. | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.998 |
HCDG_03131 | HCDG_03657 | C6HAA0 | C6HCA8 | Endoplasmic reticulum and nuclear membrane protein. | Crossover junction endonuclease mus81. | 0.877 |
HCDG_03131 | HCDG_04616 | C6HAA0 | C6HF93 | Endoplasmic reticulum and nuclear membrane protein. | Uncharacterized protein. | 0.647 |
HCDG_03131 | HCDG_09000 | C6HAA0 | C6HS19 | Endoplasmic reticulum and nuclear membrane protein. | DNA repair protein RAD1. | 0.949 |
HCDG_03319 | HCDG_00618 | C6HAT8 | C6H1N6 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Serine/threonine protein kinase. | 0.998 |
HCDG_03319 | HCDG_04616 | C6HAT8 | C6HF93 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Uncharacterized protein. | 0.647 |
HCDG_03319 | HCDG_05766 | C6HAT8 | C6HHT5 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | RNA polymerase II transcription mediator complex subunit. | 0.998 |
HCDG_03319 | HCDG_07428 | C6HAT8 | C6HMW2 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Single-stranded DNA binding protein p30 subunit. | 0.764 |
HCDG_03319 | MED17 | C6HAT8 | C6H5I0 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.998 |
HCDG_03657 | HCDG_03131 | C6HCA8 | C6HAA0 | Crossover junction endonuclease mus81. | Endoplasmic reticulum and nuclear membrane protein. | 0.877 |
HCDG_03657 | HCDG_04616 | C6HCA8 | C6HF93 | Crossover junction endonuclease mus81. | Uncharacterized protein. | 0.645 |
HCDG_03657 | HCDG_07428 | C6HCA8 | C6HMW2 | Crossover junction endonuclease mus81. | Single-stranded DNA binding protein p30 subunit. | 0.847 |
HCDG_03657 | HCDG_08381 | C6HCA8 | C6HQA0 | Crossover junction endonuclease mus81. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.965 |
HCDG_03657 | HCDG_09000 | C6HCA8 | C6HS19 | Crossover junction endonuclease mus81. | DNA repair protein RAD1. | 0.969 |
HCDG_04616 | HCDG_00618 | C6HF93 | C6H1N6 | Uncharacterized protein. | Serine/threonine protein kinase. | 0.645 |
HCDG_04616 | HCDG_03131 | C6HF93 | C6HAA0 | Uncharacterized protein. | Endoplasmic reticulum and nuclear membrane protein. | 0.647 |
HCDG_04616 | HCDG_03319 | C6HF93 | C6HAT8 | Uncharacterized protein. | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.647 |