STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCDG_05883D-ser_dehydrat domain-containing protein. (465 aa)    
Predicted Functional Partners:
HCDG_04027
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
    
  0.745
HCDG_01332
Polysaccharide deacetylase.
    
 0.729
HCDG_04496
Hydrophobin 1.
    
 0.729
HCDG_04619
Chitin deacetylase.
    
 0.729
VPS10
Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity); Belongs to the VPS10-related sortilin family.
    
 0.600
HCDG_00613
60S ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
   
 
  0.495
HCDG_03465
Protein kinase domain-containing protein.
    
 0.488
HCDG_02102
Uncharacterized protein.
    
  0.446
HCDG_01525
Uncharacterized protein.
    
  0.446
HCDG_06320
Vacuolar membrane protein.
    
  0.446
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.