STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCDG_08201Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (121 aa)    
Predicted Functional Partners:
HCDG_00784
Transcription initiation protein spt5.
    
 0.999
HCDG_04348
RNA polymerase II subunit 3.
   
 0.998
HCDG_07035
RNA polymerase II subunit 7.
   
 0.998
HCDG_08495
Polymerase II polypeptide D.
   
 0.997
HCDG_01426
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
   
 0.996
HCDG_04003
RNA polymerase subunit.
   
 0.996
HCDG_03422
DNA-directed RNA polymerase II.
   
 0.996
HCDG_03215
DNA-directed RNA polymerase I.
   
 0.995
HCDG_06073
Metallothionein-I gene transcription activator.
   
 0.995
HCDG_08020
DNA-directed RNA polymerase.
   
 0.994
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.