STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY84922.1Hydroxymethylbilane synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)    
Predicted Functional Partners:
APY87023.1
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
APY87024.1
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
APY89252.1
uroporphyrinogen-III C-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
APY88042.1
uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
APY85808.1
Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.981
APY87026.1
glutamyl-tRNA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.971
APY87025.1
Hydroxymethylbilane synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.918
APY87007.1
Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.915
APY90738.1
Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.814
APY85869.1
precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.727
Your Current Organism:
Streptomyces silaceus
NCBI taxonomy Id: 545123
Other names: DSM 41861, LDDC 6638-99, NRRL B-24166, S. silaceus, Streptomyces silaceus Labeda et al. 2009, Streptomyces sp. NRRL B-24166
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