STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY85972.1Citrate synthase/methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)    
Predicted Functional Partners:
APY90729.1
Aconitate hydratase 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
APY86773.1
Catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
APY86786.1
succinate--CoA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
APY85973.1
Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.983
APY86605.1
Fumarate hydratase; Catalyzes the formation of malate from fumerate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.983
APY86785.1
succinate--CoA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.981
APY87868.1
Phosphoenolpyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.969
aspA
Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.962
APY85612.1
Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.961
Your Current Organism:
Streptomyces silaceus
NCBI taxonomy Id: 545123
Other names: DSM 41861, LDDC 6638-99, NRRL B-24166, S. silaceus, Streptomyces silaceus Labeda et al. 2009, Streptomyces sp. NRRL B-24166
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