STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY86815.1IMP dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)    
Predicted Functional Partners:
APY86803.1
Glutamine-hydrolyzing GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
APY87230.1
Adenylosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
APY86781.1
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.992
APY86814.1
Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
0.985
APY89335.1
Bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.974
APY86047.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.970
APY87088.1
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.966
APY85368.1
Molecular chaperone HtpG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.960
APY87551.1
Bifunctional metallophosphatase/5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.960
APY88814.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.960
Your Current Organism:
Streptomyces silaceus
NCBI taxonomy Id: 545123
Other names: DSM 41861, LDDC 6638-99, NRRL B-24166, S. silaceus, Streptomyces silaceus Labeda et al. 2009, Streptomyces sp. NRRL B-24166
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