STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APY88727.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)    
Predicted Functional Partners:
APY91140.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.953
APY86047.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.926
APY88382.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.819
APY88725.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.713
APY91139.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
APY88729.1
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.656
APY88726.1
Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.595
APY88096.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.476
APY86604.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.459
APY91004.1
Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.435
Your Current Organism:
Streptomyces silaceus
NCBI taxonomy Id: 545123
Other names: DSM 41861, LDDC 6638-99, NRRL B-24166, S. silaceus, Streptomyces silaceus Labeda et al. 2009, Streptomyces sp. NRRL B-24166
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.