STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sts1Nucleus-associated proteasomal ubiquitin-dependent protein catabolic process; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins. (279 aa)    
Predicted Functional Partners:
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]
    
 0.913
ST47_g3247
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.816
ST47_g9049
WD_REPEATS_REGION domain-containing protein.
   
  0.787
ST47_g6166
CLP1_P domain-containing protein.
   
 
 0.717
ST47_g10070
Ipi1_N domain-containing protein.
   
 
  0.715
ST47_g4802
Ribosome.
   
 0.707
ST47_g381
Ribosome.
   
 0.707
ST47_g6514
ATP binding.
 
 
  
 0.694
ST47_g4184
Structural constituent of ribosome.
   
  0.683
ST47_g1805
Exonuclease.
   
 0.674
Your Current Organism:
Ascochyta rabiei
NCBI taxonomy Id: 5454
Other names: A. rabiei, CBS 237.37, Didymella rabiei, Mycosphaerella rabiei, Mycosphaerella rabiei Kovacheski, Phoma rabiei, Zythia rabiei
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