STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)    
Predicted Functional Partners:
metE_1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.967
yitJ
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
  
 
 0.901
dapL
LL-diaminopimelate aminotransferase.
  
 0.893
mdeA_2
Methionine gamma-lyase.
   
 0.889
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
  
 
 0.887
metE_4
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.884
metE_2
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.872
metE_3
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.872
metE_5
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 0.872
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
  
 0.829
Your Current Organism:
Oceanobacillus oncorhynchi
NCBI taxonomy Id: 545501
Other names: JCM 12661, NCIMB 14022, O. oncorhynchi, Oceanobacillus oncorhynchi Yumoto et al. 2005 emend. Romano et al. 2006, strain R-2
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