STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbVAnti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family. (110 aa)    
Predicted Functional Partners:
rsbW
Serine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 0.999
sigB
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.995
rsbU
Phosphoserine phosphatase RsbU.
 
 0.988
CEI82537.1
Stage II sporulation protein E (SpoIIE).
 
 0.981
fliN
Flagellar motor switch protein FliN.
  
   0.933
rsbT_2
Serine/threonine-protein kinase RsbT.
 
 0.924
rsbT_1
Serine/threonine-protein kinase RsbT.
 
 0.895
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 0.867
yfkM
General stress protein 18.
   
    0.820
fliG
Flagellar motor switch protein FliG.
  
   0.803
Your Current Organism:
Oceanobacillus oncorhynchi
NCBI taxonomy Id: 545501
Other names: JCM 12661, NCIMB 14022, O. oncorhynchi, Oceanobacillus oncorhynchi Yumoto et al. 2005 emend. Romano et al. 2006, strain R-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.