Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iscS_2Cysteine desulfurase. (380 aa)    
Predicted Functional Partners:
thiI
Putative tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.995
nifU
NifU-like protein.
 
 0.985
moeB_1
Molybdopterin-synthase adenylyltransferase.
   
 0.944
glpE_3
Thiosulfate sulfurtransferase GlpE; Belongs to the sulfur carrier protein TusA family.
   
 
 0.940
sseA_1
3-mercaptopyruvate sulfurtransferase.
   
 0.920
iscS_1
Cysteine desulfurase.
  
  
 
0.914
erpA
Iron-sulfur cluster insertion protein ErpA; Belongs to the HesB/IscA family.
 
 
 0.847
cymR
HTH-type transcriptional regulator CymR.
  
  
 0.797
nsrR
HTH-type transcriptional repressor NsrR.
  
  
 0.785
acpA
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.770
Your Current Organism:
Oceanobacillus oncorhynchi
NCBI taxonomy Id: 545501
Other names: JCM 12661, NCIMB 14022, O. oncorhynchi, Oceanobacillus oncorhynchi Yumoto et al. 2005 emend. Romano et al. 2006, strain R-2
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