SDS48799.1 protein (Paraoerskovia marina) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SDS48799.1

Glyoxylase, beta-lactamase superfamily II. (236 aa)

Predicted Functional Partners:

SDS55243.1

0.897

SDR93420.1

0.819

SDS79540.1

0.759

SDS48841.1

0.737

SDS48702.1

0.644

SDS48746.1

0.625

SDR77412.1

0.548

SDS92845.1

0.548

acpP

0.514

SDR85272.1

0.483

Your Current Organism:

Paraoerskovia marina

NCBI taxonomy Id: 545619
Other names: DSM 21750, DSM 22126 [[Koreibacter algae]], JCM 17443 [[Koreibacter algae]], KCTC 13436 [[Koreibacter algae]], Koreibacter algae, Koreibacter algae Lee and Lee 2010, Micrococcineae bacterium DSW-2, NBRC 104352, P. marina, Paraoerskovia marina Khan et al. 2009 emend. Schumann et al. 2013, strain CTT-37, strain DSW-2 [[Koreibacter algae]]

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDR77412.1	SDR85272.1	SAMN04489860_0008	SAMN04489860_0219	Rhodanese-related sulfurtransferase.	Isopalmitoylresorcinol synthase.	0.541
SDR77412.1	SDS48746.1	SAMN04489860_0008	SAMN04489860_1662	Rhodanese-related sulfurtransferase.	Peptidyl-prolyl cis-trans isomerase B (cyclophilin B).	0.627
SDR77412.1	SDS48799.1	SAMN04489860_0008	SAMN04489860_1663	Rhodanese-related sulfurtransferase.	Glyoxylase, beta-lactamase superfamily II.	0.548
SDR77412.1	SDS55243.1	SAMN04489860_0008	SAMN04489860_1805	Rhodanese-related sulfurtransferase.	Glyoxylase, beta-lactamase superfamily II.	0.421
SDR77412.1	acpP	SAMN04489860_0008	SAMN04489860_1492	Rhodanese-related sulfurtransferase.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.579
SDR85272.1	SDR77412.1	SAMN04489860_0219	SAMN04489860_0008	Isopalmitoylresorcinol synthase.	Rhodanese-related sulfurtransferase.	0.541
SDR85272.1	SDR93420.1	SAMN04489860_0219	SAMN04489860_0419	Isopalmitoylresorcinol synthase.	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	0.573
SDR85272.1	SDS48799.1	SAMN04489860_0219	SAMN04489860_1663	Isopalmitoylresorcinol synthase.	Glyoxylase, beta-lactamase superfamily II.	0.483
SDR85272.1	SDS55243.1	SAMN04489860_0219	SAMN04489860_1805	Isopalmitoylresorcinol synthase.	Glyoxylase, beta-lactamase superfamily II.	0.483
SDR85272.1	SDS79540.1	SAMN04489860_0219	SAMN04489860_2387	Isopalmitoylresorcinol synthase.	Adenylyltransferase and sulfurtransferase.	0.541
SDR85272.1	SDS92845.1	SAMN04489860_0219	SAMN04489860_2735	Isopalmitoylresorcinol synthase.	Rhodanese-related sulfurtransferase.	0.541
SDR85272.1	acpP	SAMN04489860_0219	SAMN04489860_1492	Isopalmitoylresorcinol synthase.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.800
SDR93420.1	SDR85272.1	SAMN04489860_0419	SAMN04489860_0219	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	Isopalmitoylresorcinol synthase.	0.573
SDR93420.1	SDS48746.1	SAMN04489860_0419	SAMN04489860_1662	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	Peptidyl-prolyl cis-trans isomerase B (cyclophilin B).	0.833
SDR93420.1	SDS48799.1	SAMN04489860_0419	SAMN04489860_1663	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	Glyoxylase, beta-lactamase superfamily II.	0.819
SDR93420.1	SDS55243.1	SAMN04489860_0419	SAMN04489860_1805	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	Glyoxylase, beta-lactamase superfamily II.	0.819
SDR93420.1	SDS79540.1	SAMN04489860_0419	SAMN04489860_2387	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	Adenylyltransferase and sulfurtransferase.	0.834
SDR93420.1	acpP	SAMN04489860_0419	SAMN04489860_1492	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.675
SDS48702.1	SDS48746.1	SAMN04489860_1661	SAMN04489860_1662	Protein of unknown function.	Peptidyl-prolyl cis-trans isomerase B (cyclophilin B).	0.838
SDS48702.1	SDS48799.1	SAMN04489860_1661	SAMN04489860_1663	Protein of unknown function.	Glyoxylase, beta-lactamase superfamily II.	0.644

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Network Stats

number of nodes:

11

number of edges:

52

average node degree:

9.45

avg. local clustering coefficient:

0.958

expected number of edges:

33

PPI enrichment p-value:

0.00092

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006099

Tricarboxylic acid cycle

3 of 3

2.15

1.42

0.0020

GO:0006091

Generation of precursor metabolites and energy

8 of 76

1.17

1.35

5.90e-06

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008948

Oxaloacetate decarboxylase activity

2 of 2

2.15

0.74

0.0433

GO:0004775

succinate-CoA ligase (ADP-forming) activity

2 of 2

2.15

0.74

0.0433

GO:0004471

Malate dehydrogenase (decarboxylating) (NAD+) activity

2 of 2

2.15

0.74

0.0433

GO:0016616

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

3 of 12

1.55

0.68

0.0433

GO:0016491

Oxidoreductase activity

6 of 146

0.76

0.43

0.0433

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 421

0.48

0.33

0.0243

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:106

Mixed, incl. Tricarboxylic acid cycle, and Malic enzyme activity

7 of 11

1.95

3.96

2.59e-10

CL:102

Mixed, incl. Citrate cycle (TCA cycle), and Tricarboxylic acid cycle

9 of 29

1.64

3.31

1.97e-11

CL:99

Microbial metabolism in diverse environments, and Lipid metabolic process

10 of 86

1.21

1.82

3.47e-10

CL:108

Malic enzyme activity, and AMP-binding, conserved site

3 of 5

1.93

1.69

0.00036

CL:146

Citrate cycle (TCA cycle)

2 of 5

1.75

0.85

0.0218

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00020

Citrate cycle (TCA cycle)

4 of 14

1.6

1.66

0.00012

map01200

Carbon metabolism

8 of 75

1.18

1.47

6.16e-07

map00620

Pyruvate metabolism

5 of 31

1.35

1.42

9.41e-05

map01120

Microbial metabolism in diverse environments

7 of 126

0.89

0.82

0.00016

map01110

Biosynthesis of secondary metabolites

7 of 179

0.74

0.59

0.0012

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042709

succinate-CoA ligase complex

2 of 2

2.15

0.9

0.0214

GOCC:0005737

Cytoplasm

9 of 310

0.61

0.46

0.0034

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0816

Tricarboxylic acid cycle

3 of 3

2.15

1.64

0.00070

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