STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abrBTransition state regulatory protein AbrB. (94 aa)    
Predicted Functional Partners:
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.794
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
    0.726
BMQ_1678
Spore germination protein GerA.
  
   
 0.704
gerAA
Spore germination protein A1.
  
   
 0.698
sigG
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.696
BMQ_1219
Spore germination protein GerA.
  
   
 0.684
gerKA
Spore germination protein KA.
  
   
 0.681
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.675
BMQ_2245
Spore germination protein GerA.
  
   
 0.665
spoVAD-2
Stage V sporulation protein AD.
  
     0.665
Your Current Organism:
Bacillus megaterium QM B1551
NCBI taxonomy Id: 545693
Other names: B. megaterium QM B1551, Bacillus megaterium str. QM B1551, Bacillus megaterium strain QM B1551
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