STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cotPSpore coat protein P; Belongs to the small heat shock protein (HSP20) family. (157 aa)    
Predicted Functional Partners:
BMQ_2016
Small heat shock protein; Belongs to the small heat shock protein (HSP20) family.
  
     0.708
clpC
ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.
  
 
 0.639
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.639
clpE
ATP-dependent Clp protease, ATP-binding subunit ClpE; Belongs to the ClpA/ClpB family.
  
 
 0.639
BMQ_2574
Conserved hypothetical protein.
       0.598
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.552
BMQ_2576
Hypothetical protein.
       0.506
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.503
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.476
BMQ_3486
Conserved hypothetical protein.
  
 
 0.475
Your Current Organism:
Bacillus megaterium QM B1551
NCBI taxonomy Id: 545693
Other names: B. megaterium QM B1551, Bacillus megaterium str. QM B1551, Bacillus megaterium strain QM B1551
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