| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BMQ_0953 | BMQ_1706 | BMQ_0953 | BMQ_1706 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | 0.630 |
| BMQ_0953 | alsS | BMQ_0953 | BMQ_0789 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 0.652 |
| BMQ_0953 | ilvB | BMQ_0953 | BMQ_4700 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit, biosynthetic type. | 0.629 |
| BMQ_0953 | ilvC | BMQ_0953 | BMQ_4698 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.990 |
| BMQ_0953 | ilvD | BMQ_0953 | BMQ_2510 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.896 |
| BMQ_0953 | ilvH | BMQ_0953 | BMQ_4699 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.940 |
| BMQ_0953 | leuA | BMQ_0953 | BMQ_4697 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.938 |
| BMQ_0953 | leuB | BMQ_0953 | BMQ_4696 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.969 |
| BMQ_0953 | leuC | BMQ_0953 | BMQ_4695 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.581 |
| BMQ_0953 | leuD | BMQ_0953 | BMQ_4694 | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.613 |
| BMQ_1706 | BMQ_0953 | BMQ_1706 | BMQ_0953 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | Putative acetohydroxyacid synthase large subunit; Belongs to the TPP enzyme family. | 0.630 |
| BMQ_1706 | alsS | BMQ_1706 | BMQ_0789 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 0.620 |
| BMQ_1706 | ilvB | BMQ_1706 | BMQ_4700 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit, biosynthetic type. | 0.630 |
| BMQ_1706 | ilvC | BMQ_1706 | BMQ_4698 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.991 |
| BMQ_1706 | ilvD | BMQ_1706 | BMQ_2510 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.909 |
| BMQ_1706 | ilvH | BMQ_1706 | BMQ_4699 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.930 |
| BMQ_1706 | leuA | BMQ_1706 | BMQ_4697 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.943 |
| BMQ_1706 | leuB | BMQ_1706 | BMQ_4696 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.974 |
| BMQ_1706 | leuC | BMQ_1706 | BMQ_4695 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.636 |
| BMQ_1706 | leuD | BMQ_1706 | BMQ_4694 | Thiamine pyrophosphate enzyme domain protein; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.638 |
