Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
Databases
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[Homology]
Score
AEF86132.1Hypothetical protein; Identified by glimmer; putative. (327 aa)    
Predicted Functional Partners:
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.754
AEF84945.1
Galactokinase; Identified by match to protein family HMM PF00288; Belongs to the GHMP kinase family.
       0.590
AEF86765.1
Putative tetratricopeptide TPR_2 repeat protein.
       0.487
AEF84002.1
Tetratricopeptide repeat domain protein; Identified by match to protein family HMM PF07719.
       0.487
AEF85640.1
Putative lipoprotein.
       0.487
AEF86402.1
Probable extracellular nuclease; Identified by match to protein family HMM PF02415; match to protein family HMM PF03781.
     
 0.480
AEF83672.1
Probable extracellular nuclease.
     
 0.480
dinB-2
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.470
AEF83823.1
RNA polymerase sigma-24 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.444
AEF85672.1
Sigma-24, ECF subfamily; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.444
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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