STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
gltB
Glutamate synthase, large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
    
 0.899
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
 
    
 0.860
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.839
AEF84988.1
Glutamate synthase [NADH] (nadh-gogat); Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317.
    
 0.817
AEF84692.1
Glutamine synthetase (Glutamate--ammonia ligase) (GS); Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
     
  0.800
AEF84876.1
Conserved hypothetical protein.
       0.762
AEF84219.1
Acetyltransferase; Identified by match to protein family HMM PF00583.
       0.715
AEF85115.1
Phosphopantothenoylcysteine synthetase/decarboxylase; Identified by match to protein family HMM PF04127.
       0.704
AEF85492.1
Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenatemetabolism flavoprotein); Identified by match to protein family HMM PF02441.
       0.704
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.