STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (333 aa)    
Predicted Functional Partners:
AEF85381.1
uroporphyrinogen-III synthase/methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469.
 0.999
hemB
Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.
 
 0.999
AEF84001.1
Siroheme synthase; Identified by match to protein family HMM TIGR01470.
  
 0.963
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
       0.791
AEF86814.1
Mov34/MPN/PAD-1; Identified by match to protein family HMM PF01398.
       0.791
AEF85958.1
Conserved hypothetical protein.
  
  
 0.726
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
   
    0.718
cobM
Precorrin-4 C(11)-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465.
   
 0.649
AEF86106.1
Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
 
  
 0.625
AEF84480.1
Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260.
  
    0.569
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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