STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdDAnaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF03477; match to protein family HMM TIGR02487. (775 aa)    
Predicted Functional Partners:
nrdG
Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
 
 
 0.991
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
 0.920
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.908
ndk-2
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.906
AEF84702.1
Adenylate/guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211; match to protein family HMM PF05226.
     
  0.900
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
     
  0.900
AEF85176.1
Putative adenylate cyclase 2 (ATP pyrophosphate-lyase 2) (Adenylylcyclase 2) (AC2); Identified by match to protein family HMM PF00072; match to protein family HMM PF00211.
     
  0.900
AEF86214.1
Adenylate/guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00211; match to protein family HMM PF07719.
     
  0.900
AEF84401.1
GTP diphosphokinase; Identified by match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691.
     
  0.900
AEF84110.1
Putative adenylate cyclase 2 (ATP pyrophosphate-lyase 2) (Adenylylcyclase 2) (AC2); Identified by match to protein family HMM PF00072; match to protein family HMM PF00211.
     
  0.900
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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