node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEF83705.1 | eno | TREPR_0394 | TREPR_0776 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.894 |
AEF83705.1 | fba | TREPR_0394 | TREPR_1085 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. | 0.983 |
AEF83705.1 | gap | TREPR_0394 | TREPR_2454 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.900 |
AEF83705.1 | pfkA | TREPR_0394 | TREPR_0608 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.469 |
AEF83705.1 | pfkA-2 | TREPR_0394 | TREPR_3551 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.469 |
AEF83705.1 | pfp | TREPR_0394 | TREPR_1621 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.469 |
AEF83705.1 | pgi | TREPR_0394 | TREPR_2249 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. | 0.960 |
AEF83705.1 | pyk | TREPR_0394 | TREPR_0649 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.901 |
AEF83705.1 | tpiA | TREPR_0394 | TREPR_2452 | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.989 |
eno | AEF83705.1 | TREPR_0776 | TREPR_0394 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | 0.894 |
eno | fba | TREPR_0776 | TREPR_1085 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. | 0.975 |
eno | gap | TREPR_0776 | TREPR_2454 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.938 |
eno | pfkA | TREPR_0776 | TREPR_0608 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.810 |
eno | pfkA-2 | TREPR_0776 | TREPR_3551 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.810 |
eno | pfp | TREPR_0776 | TREPR_1621 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.810 |
eno | pgi | TREPR_0776 | TREPR_2249 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. | 0.978 |
eno | pyk | TREPR_0776 | TREPR_0649 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.997 |
eno | tpiA | TREPR_0776 | TREPR_2452 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.987 |
fba | AEF83705.1 | TREPR_1085 | TREPR_0394 | Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. | Glyceraldehyde-3-phosphate dehydrogenase, type II; Identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01546. | 0.983 |
fba | eno | TREPR_1085 | TREPR_0776 | Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.975 |