STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF84401.1GTP diphosphokinase; Identified by match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691. (755 aa)    
Predicted Functional Partners:
AEF85297.1
Putative exopolyphosphatase; Identified by match to protein family HMM PF01966; match to protein family HMM PF02541.
  
 
 0.921
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
   
 
 0.916
AEF86267.1
RelA/SpoT domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF04607; match to protein family HMM PF07719.
    
 0.914
ndk-2
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.911
AEF84654.1
RelA/SpoT domain protein; Identified by match to protein family HMM PF04607.
    
 0.911
AEF85895.1
Vitamin B12-dependent ribonucleotide reductase (Ribonucleoside-diphosphate reductase NrdJ); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.903
nrdD
Anaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF03477; match to protein family HMM TIGR02487.
     
  0.900
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.833
hemK
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.819
rplX
Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
   0.806
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.