STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ogtmethylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (171 aa)    
Predicted Functional Partners:
AEF84517.1
methylated-DNA--[protein]-cysteine S-methyltransferase; Identified by match to protein family HMM PF00730.
 
  
 0.986
AEF85050.1
methylphosphotriester-DNA alkyltransferase; Identified by match to protein family HMM PF00165; match to protein family HMM PF02805.
  
 0.984
AEF86815.1
Putative lipoprotein.
       0.775
AEF84149.1
DNA-3-methyladenine glycosylase 1; Identified by match to protein family HMM PF03352.
   
 0.770
AEF84122.1
Putative universal stress protein family; Identified by match to protein family HMM PF00582.
  
    0.565
AEF83555.1
Transcriptional regulator.
  
    0.565
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.539
rpoD
RNA polymerase sigma factor RpoD (Sigma-70); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
   0.451
AEF83809.1
Hypothetical protein; Identified by glimmer; putative.
       0.437
AEF84208.1
Identified by match to protein family HMM PF07556.
       0.437
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.