STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF86387.1Conserved hypothetical protein; Identified by match to protein family HMM PF00483; match to protein family HMM TIGR01656; match to protein family HMM TIGR01662. (435 aa)    
Predicted Functional Partners:
AEF84176.1
Phosphoheptose isomerase; Identified by match to protein family HMM PF01380.
  
 0.996
AEF84934.1
D-glycero-D-manno-heptose 7-phosphate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544.
 
  
 0.992
AEF85038.1
Histidine biosynthesis bifunctional protein hisIE; Identified by match to protein family HMM PF00977; match to protein family HMM PF01502; match to protein family HMM PF01503; match to protein family HMM TIGR03188; Belongs to the HisA/HisF family.
  
 
 0.977
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
    
 0.976
AEF86609.1
Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase) (GMP); Identified by match to protein family HMM PF00483.
  
 
 0.956
selB
Selenocysteine-specific translation elongation factor; Identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09107; match to protein family HMM TIGR00231; match to protein family HMM TIGR00475.
   
 0.937
manA
Mannose-6-phosphate isomerase, class I; Identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218.
  
 0.922
AEF84644.1
Hexokinase; Identified by match to protein family HMM PF00349; match to protein family HMM PF03727.
   
 
 0.916
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
 
 0.903
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.889
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.