STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF84000.1Conserved hypothetical protein; Identified by match to protein family HMM PF08308. (522 aa)    
Predicted Functional Partners:
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.817
AEF84429.1
Serine/threonine kinase; Identified by match to protein family HMM PF03781.
 
     0.747
AEF85715.1
XylR; Identified by match to protein family HMM PF03781.
  
     0.741
AEF86402.1
Probable extracellular nuclease; Identified by match to protein family HMM PF02415; match to protein family HMM PF03781.
  
     0.686
lepB_1
Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
 
     0.669
AEF83897.1
HemN C- region family; Identified by match to protein family HMM PF04055; match to protein family HMM PF06969.
       0.551
AEF86454.1
Hypothetical protein; Identified by glimmer; putative.
       0.535
lepB_2
Signal peptidase I; Identified by match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
       0.526
AEF86117.1
Hypothetical protein; Identified by glimmer; putative.
  
     0.456
AEF85732.1
Conserved hypothetical protein; Identified by match to protein family HMM PF03781.
  
     0.450
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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