| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEF84280.1 | AEF85229.1 | TREPR_2793 | TREPR_2794 | Regulatory protein, ArsR; Identified by match to protein family HMM PF01022. | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | 0.553 |
| AEF84280.1 | AEF86027.1 | TREPR_2793 | TREPR_3715 | Regulatory protein, ArsR; Identified by match to protein family HMM PF01022. | Identified by match to protein family HMM PF02597. | 0.461 |
| AEF84280.1 | thiI | TREPR_2793 | TREPR_2795 | Regulatory protein, ArsR; Identified by match to protein family HMM PF01022. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.550 |
| AEF84798.1 | thiI | TREPR_1941 | TREPR_2795 | Putative methyltransferase nsun4 (Nol1/nop2/sun domainfamily member 4); Identified by match to protein family HMM PF01189; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.796 |
| AEF85080.1 | argS | TREPR_0498 | TREPR_3443 | N6-adenine-specific DNA methylase; Identified by match to protein family HMM PF01170. | arginine--tRNA ligase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | 0.526 |
| AEF85080.1 | thiI | TREPR_0498 | TREPR_2795 | N6-adenine-specific DNA methylase; Identified by match to protein family HMM PF01170. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.475 |
| AEF85229.1 | AEF84280.1 | TREPR_2794 | TREPR_2793 | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | Regulatory protein, ArsR; Identified by match to protein family HMM PF01022. | 0.553 |
| AEF85229.1 | AEF86027.1 | TREPR_2794 | TREPR_3715 | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | Identified by match to protein family HMM PF02597. | 0.843 |
| AEF85229.1 | iscS | TREPR_2794 | TREPR_2724 | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | Cysteine desulfurase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | 0.922 |
| AEF85229.1 | thiI | TREPR_2794 | TREPR_2795 | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.995 |
| AEF86027.1 | AEF84280.1 | TREPR_3715 | TREPR_2793 | Identified by match to protein family HMM PF02597. | Regulatory protein, ArsR; Identified by match to protein family HMM PF01022. | 0.461 |
| AEF86027.1 | AEF85229.1 | TREPR_3715 | TREPR_2794 | Identified by match to protein family HMM PF02597. | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | 0.843 |
| AEF86027.1 | iscS | TREPR_3715 | TREPR_2724 | Identified by match to protein family HMM PF02597. | Cysteine desulfurase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | 0.843 |
| AEF86027.1 | metG | TREPR_3715 | TREPR_1795 | Identified by match to protein family HMM PF02597. | methionyl-tRNA synthetase (Methionine--tRNA ligase)(MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.561 |
| AEF86027.1 | thiI | TREPR_3715 | TREPR_2795 | Identified by match to protein family HMM PF02597. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.559 |
| AEF86933.1 | thiI | TREPR_3449 | TREPR_2795 | Conserved hypothetical protein; Identified by match to protein family HMM PF04327. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.436 |
| argS | AEF85080.1 | TREPR_3443 | TREPR_0498 | arginine--tRNA ligase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | N6-adenine-specific DNA methylase; Identified by match to protein family HMM PF01170. | 0.526 |
| argS | metG | TREPR_3443 | TREPR_1795 | arginine--tRNA ligase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | methionyl-tRNA synthetase (Methionine--tRNA ligase)(MetRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.963 |
| argS | thiI | TREPR_3443 | TREPR_2795 | arginine--tRNA ligase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.481 |
| iscS | AEF85229.1 | TREPR_2724 | TREPR_2794 | Cysteine desulfurase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | Cysteine desulfurase; Identified by match to protein family HMM PF00266. | 0.922 |