Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hydBProtein AegA; Identified by match to protein family HMM PF00037. (181 aa)    
Predicted Functional Partners:
fdhA
Formate dehydrogenase, alpha subunit; Identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.993
hydA1
Iron hydrogenase 1 ([Fe] hydrogenase) (Fe-onlyhydrogenase) (CpI); Identified by match to protein family HMM PF00037; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.
   
  0.981
hydN
Protein AegA; Identified by match to protein family HMM PF00037.
 
  
 
0.967
cooS
Carbon-monoxide dehydrogenase, catalytic subunit; Identified by match to protein family HMM PF03063; match to protein family HMM TIGR01702.
    
 0.911
fhs
Formate--tetrahydrofolate ligase; Identified by match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.904
AEF86186.1
Identified by match to protein family HMM PF02663.
     
  0.900
rnfB
Ferredoxin; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
 
 0.893
AEF85018.1
NADH dehydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01512.
  
   0.865
hndB3
NAD-dependent formate dehydrogenase beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM PF01512.
  
   0.865
fdhD
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
     0.863
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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