Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEF86346.1Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165. (537 aa)    
Predicted Functional Partners:
AEF86717.1
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165.
 
    
0.789
AEF85163.1
Cobalamin B12-binding domain protein; Identified by match to protein family HMM PF02310; match to protein family HMM PF02607.
 
     0.748
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.693
AEF85050.1
methylphosphotriester-DNA alkyltransferase; Identified by match to protein family HMM PF00165; match to protein family HMM PF02805.
 
     0.635
AEF83635.1
Aldehyde-alcohol dehydrogenase 2; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.628
AEF85912.1
PAS domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.
  
  
 0.608
AEF84402.1
PAS domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM PF08448; match to protein family HMM TIGR00229.
  
  
 0.592
AEF87032.1
Multi-sensor hybrid histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
  
 0.578
AEF85231.1
PAS domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
  
 0.574
AEF86977.1
Peptidase M52, hydrogen uptake protein; Identified by match to protein family HMM PF01627.
  
  
 0.574
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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