STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (301 aa)    
Predicted Functional Partners:
AEF84205.1
Dihydroorotate dehydrogenase, electron transfer subunit; Identified by match to protein family HMM PF00175.
 
 0.999
pyrC
Dihydroorotase (DHOase); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.998
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.984
pyrB
Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.959
asrB
Sulfite reductase, subunit B; Identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02911.
 
 
 0.957
carB
Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02222; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.
 
 
 0.885
hydA
Dihydropyrimidinase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02033.
 
 
 0.853
pyrF
Orotidine 5'-phosphate decarboxylase; Identified by match to protein family HMM PF00215; match to protein family HMM TIGR02127; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.845
AEF83863.1
Aspartate carbamoyltransferase, regulatory subunit; Identified by match to protein family HMM PF01948.
 
  
 0.837
AEF84988.1
Glutamate synthase [NADH] (nadh-gogat); Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317.
 
 
 0.781
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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