Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEF86322.1Conserved hypothetical protein. (407 aa)    
Predicted Functional Partners:
nifH_1
Nitrogenase iron protein; Identified by match to protein family HMM PF00142; Belongs to the NifH/BchL/ChlL family.
 
 
 0.939
AEF85470.1
Conserved hypothetical protein.
     0.931
AEF84719.1
Nitrogen fixation protein NifH/NifE; Identified by match to protein family HMM PF00142; match to protein family HMM PF00148; Belongs to the NifH/BchL/ChlL family.
 
 
 0.860
AEF85643.1
Nitrogenase iron protein NifH; Identified by match to protein family HMM PF00142; Belongs to the NifH/BchL/ChlL family.
 
 
 0.839
nifH_2
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
 
 0.749
nifB
Nitrogenase cofactor biosynthesis protein NifB; Identified by match to protein family HMM PF02579; match to protein family HMM PF04055; match to protein family HMM TIGR01290.
  
 
 0.620
AEF86973.1
Putative lipoprotein.
  
     0.436
AEF85269.1
Putative lipoprotein.
  
     0.413
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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