Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobB_1Cobyrinic Acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (459 aa)    
Predicted Functional Partners:
AEF84839.1
cobalt-precorrin-8X methylmutase; Identified by match to protein family HMM PF02570.
 
 0.989
AEF84311.1
Threonine-phosphate decarboxylase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01140.
  
 0.941
AEF83749.1
Cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF02572.
 
 
 0.940
cobB_2
Cobyrinic Acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379.
  
  
 
0.923
AEF86491.1
ATP:cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.912
AEF83599.1
ATPase, AAA family; Identified by match to protein family HMM PF07726; match to protein family HMM PF07728.
     
  0.900
AEF86059.1
Precorrin-6y C5,15-methyltransferase (decarboxylating); Identified by match to protein family HMM PF00590; match to protein family HMM PF03602; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
  
 0.899
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.888
cobQ_2
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.877
cobM
Precorrin-4 C(11)-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465.
 
  
 0.871
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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