Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEF85202.1Metallo-beta-lactamase superfamily hydrolase; Identified by match to protein family HMM PF00753. (215 aa)    
Predicted Functional Partners:
AEF86225.1
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
 
    0.804
AEF86746.1
Identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797.
  
    0.773
AEF85978.1
Phage infection protein; Identified by match to protein family HMM TIGR03061; match to protein family HMM TIGR03062.
       0.773
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family.
  
    0.542
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
    0.536
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.533
gidB
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
    0.512
AEF86548.1
NADH oxidase (noxase); Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
 0.507
AEF86027.1
Identified by match to protein family HMM PF02597.
  
 
 0.498
AEF85458.1
Conserved hypothetical protein.
       0.479
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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