STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF86225.1Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (196 aa)    
Predicted Functional Partners:
AEF85202.1
Metallo-beta-lactamase superfamily hydrolase; Identified by match to protein family HMM PF00753.
 
   
 0.805
AEF85978.1
Phage infection protein; Identified by match to protein family HMM TIGR03061; match to protein family HMM TIGR03062.
  
  
 0.796
AEF86746.1
Identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797.
       0.774
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.544
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family.
       0.533
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.533
AEF84842.1
Short chain dehydrogenase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
   
 0.509
gidB
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
     
 0.498
AEF85458.1
Conserved hypothetical protein.
       0.479
AEF86235.1
DNA or RNA helicase of superfamily II; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851.
  
     0.477
Your Current Organism:
Treponema primitia ZAS2
NCBI taxonomy Id: 545694
Other names: T. primitia ZAS-2, Treponema primitia ZAS-2, Treponema primitia str. ZAS-2, Treponema primitia strain ZAS-2, Treponema sp. ZAS-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.