STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF69507.1Peptidase, S41 family; KEGG: lwe:lwe1870 1.4e-63 ctpA; carboxy-terminal processing protease K03797; Belongs to the peptidase S41A family. (543 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.842
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
 
  0.834
EEF66173.1
KEGG: cyb:CYB_1515 4.6e-15 tetratricopeptide repeat/protein kinase domain protein K08884; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.793
EEF67667.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.764
EEF67257.1
TIGR02677 family protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.764
EEF66346.1
Collagen triple helix repeat protein; KEGG: gga:418942 2.2e-25 LOC418942; similar to Mitochondrial intermediate peptidase K01410.
  
 
 0.764
EEF66348.1
Putative protein BclA; KEGG: gga:418942 1.2e-21 LOC418942; similar to Mitochondrial intermediate peptidase K01410.
  
 
 0.764
EEF69471.1
Trypsin; KEGG: lin:lin0320 1.3e-58 similar to heat-shock protein htrA serine protease.
 
  
 0.758
EEF69509.1
Hypothetical protein.
       0.757
EEF69792.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
    
 
 0.755
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.