STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF68880.1Hypothetical protein; Psort location: Extracellular, score: 8.82. (52 aa)    
Predicted Functional Partners:
EEF68879.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.634
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
       0.625
EEF68883.1
Hypothetical protein.
       0.522
EEF68877.1
PRD domain protein; KEGG: spb:M28_Spy1064 1.3e-24 PTS system, mannitol (cryptic)-specific IIA component K00890; Psort location: Cytoplasmic, score: 8.87.
       0.505
EEF68878.1
Hypothetical protein.
       0.505
frwB-2
KEGG: eca:ECA0341 1.9e-27 PTS system, IIb component K02769; Psort location: Cytoplasmic, score: 9.98.
       0.489
EEF68876.1
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: lwe:lwe2156 1.0e-33 PTS system, fructose-specific IIA component K00890; Psort location: CytoplasmicMembrane, score: 9.49.
       0.489
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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