STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF68337.1Transcriptional regulator, TetR family. (185 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.699
EEF69623.1
Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 8.87.
  
     0.689
pth
aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.664
pyk
Pyruvate kinase; KEGG: bha:BH3163 1.5e-119 pykA; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 8.87.
   
 0.658
EEF68967.1
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
 
 0.613
EEF66727.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.604
EEF68227.1
KEGG: ava:Ava_1011 9.3e-26 short-chain dehydrogenase/reductase SDR; Psort location: Cytoplasmic, score: 9.65; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.596
EEF67226.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.586
EEF66064.1
Methyltransferase domain protein; KEGG: cvi:CV0170 2.9e-54 probable methyl transferase K00599; Psort location: Cytoplasmic, score: 8.87.
    
 0.585
EEF66189.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.576
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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