STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF68341.1Hypothetical protein; KEGG: mca:MCA2134 1.3e-17 trxA-2; thioredoxin K03672; Psort location: Cytoplasmic, score: 9.98; Belongs to the thioredoxin family. (106 aa)    
Predicted Functional Partners:
EEF68340.1
Hypothetical protein; KEGG: tte:TTE2220 8.0e-75 trxB2; thioredoxin reductase K00384; Psort location: Cytoplasmic, score: 9.98.
  
 0.985
trxB
KEGG: bcl:ABC3038 8.2e-82 trxB; thioredoxin reductase K00384; Psort location: Cytoplasmic, score: 9.98.
  
 0.940
EEF68586.1
Tat pathway signal sequence domain protein; KEGG: afu:AF0455 5.7e-58 noxB-1; NADH oxidase (NoxB-1) K00359; Psort location: Cytoplasmic, score: 8.87.
  
 0.928
EEF68346.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: afu:AF0455 1.1e-24 noxB-1; NADH oxidase (NoxB-1) K00359.
  
 0.928
EEF68347.1
Tat pathway signal sequence domain protein; KEGG: afu:AF1262 5.3e-13 noxB-2; NADH oxidase (NoxB-2) K00359; Psort location: Cytoplasmic, score: 8.87.
  
 0.928
EEF68969.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.889
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.867
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
 0.866
pyk
Pyruvate kinase; KEGG: bha:BH3163 1.5e-119 pykA; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 8.87.
   
 0.863
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
 
 0.857
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.