STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (312 aa)    
Predicted Functional Partners:
mraZ
Protein MraZ; Psort location: Cytoplasmic, score: 8.87; Belongs to the MraZ family.
  
 0.991
pbpB
Penicillin-binding protein 2B; KEGG: tte:TTE1916 5.5e-44 ftsI4; Cell division protein FtsI/penicillin-binding protein 2 K03587; Psort location: CytoplasmicMembrane, score: 9.82.
 
  
 0.925
EEF68114.1
PASTA domain protein; KEGG: bca:BCE_3904 0.00011 serine/threonine protein kinase K08884.
  
  
 0.899
EEF68115.1
KEGG: tte:TTE1916 9.5e-104 ftsI4; Cell division protein FtsI/penicillin-binding protein 2 K03587; Psort location: CytoplasmicMembrane, score: 9.82.
  
 0.882
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
 
 
 0.852
rpsP
Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.843
rpsI
Ribosomal protein S9; Psort location: Cytoplasmic, score: 8.87; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.830
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.829
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
 
 0.822
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
 
 0.821
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.