STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF66796.1Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (370 aa)    
Predicted Functional Partners:
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 0.911
rlmN
23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
   
 0.796
EEF66795.1
MazG nucleotide pyrophosphohydrolase domain protein; Psort location: Cytoplasmic, score: 8.87.
       0.790
EEF69758.1
Tat pathway signal sequence domain protein; KEGG: cno:NT01CX_0497 1.4e-05 pflC; pyruvate formate-lyase K00538.
  
 
 0.767
EEF67872.1
Hypothetical protein; KEGG: mac:MA2078 0.0010 flavodoxin K00230.
    
 0.757
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737.
 
  
 0.731
EEF68150.1
Hydrolase, alpha/beta domain protein; KEGG: bce:BC1788 9.7e-47 lysophospholipase L2 K01048; Psort location: Cytoplasmic, score: 8.87.
 
  
  0.730
EEF68391.1
Putative radical SAM protein YgiQ; KEGG: vfi:VF1726 1.9e-128 hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.723
EEF66370.1
Radical SAM domain protein; KEGG: gka:GK0942 1.7e-74 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.723
EEF68079.1
Hypothetical protein.
    
 0.721
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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