STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABAnti-sigma F factor; KEGG: bha:BH1537 1.7e-33 spoIIAB; anti-sigma F factor (stage II sporulation protein AB) K06379; Psort location: Cytoplasmic, score: 8.87. (142 aa)    
Predicted Functional Partners:
EEF66419.1
STAS domain protein; KEGG: ava:Ava_0744 0.0079 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.999
sigF
RNA polymerase sigma-F factor; KEGG: reh:H16_A2373 3.1e-14 rpoS; DNA-directed RNA polymerase sigma subunit (sigma38) K00960; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.
 
 
 0.994
EEF67153.1
KEGG: cpe:CPE2473 1.3e-07 spoIIE; stage II sprulation protein E K06382; Psort location: Cytoplasmic, score: 8.87.
  
 0.983
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.977
EEF69308.1
Response regulator receiver domain protein; KEGG: syn:slr2099 1.1e-16 hik40; two-component hybrid histidine kinase K02486; Psort location: Cytoplasmic, score: 9.98.
  
 0.936
EEF69304.1
Diguanylate cyclase (GGDEF) domain protein; KEGG: vfi:VF0494 6.6e-46 sensory transduction protein kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.936
EEF69296.1
Hpt domain protein; KEGG: abo:ABO_1811 2.1e-05 two-component hybrid sensor and regulator; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.922
EEF68829.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.922
EEF67584.1
Cyclic diguanylate phosphodiesterase (EAL) domain protein; KEGG: vfi:VF0087 3.6e-38 sensory transduction protein kinase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.907
EEF67439.1
Hypothetical protein.
  
 
 0.906
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.