STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (297 aa)    
Predicted Functional Partners:
thrC
Threonine synthase; KEGG: blo:BL1036 3.8e-107 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
EEF66287.1
KEGG: ldb:Ldb1350 5.3e-55 homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
EEF66288.1
Amino acid kinase family; KEGG: ldb:Ldb1349 2.8e-120 ask; aspartate kinase K00928; Psort location: Cytoplasmic, score: 8.87; Belongs to the aspartokinase family.
 
 0.983
EEF66284.1
ACT domain protein; KEGG: ctc:CTC00116 4.7e-31 chorismate mutase K06209; Belongs to the UPF0735 family.
 
  
  0.956
EEF66078.1
Amino acid kinase family; KEGG: bca:BCE_3837 3.1e-41 dapG; aspartate kinase I K00928; Psort location: Cytoplasmic, score: 8.87.
 
 0.949
EEF66307.1
Putative L-serine ammonia-lyase; KEGG: fnu:FN1106 6.9e-85 l-serine dehydratase K01752; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.940
EEF69283.1
Putative diaminopropionate ammonia-lyase; KEGG: ppr:PBPRA1993 6.6e-80 putative threonine dehydratase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.938
purM
KEGG: lwe:lwe1785 3.0e-116 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.87.
    
 0.916
asd-2
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.909
EEF67373.1
Hypothetical protein.
   
 0.848
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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