Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY29623.1DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (648 aa)    
Predicted Functional Partners:
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
  
 0.828
EKY29621.1
ATP-dependent protease, Lon family; KEGG: cpr:CPR_2649 1.4e-250 ATP-dependent protease; K01338 ATP-dependent Lon protease; Psort location: Cytoplasmic, score: 9.97.
       0.704
EKY28545.1
YbbR-like protein.
  
   
 0.649
EKY29624.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.631
EKY29628.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
     0.599
EKY29620.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
    0.588
dacA
TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
  
   
 0.518
tmcAL
Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
     0.516
EKY27781.1
Methyltransferase small domain protein; KEGG: ctc:CTC00225 1.6e-80 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50.
  
     0.498
rpsR
Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.497
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
Server load: low (38%) [HD]