STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKY29458.1KEGG: cbe:Cbei_4323 3.1e-157 DNA topoisomerase IV subunit A K02621; Psort location: Cytoplasmic, score: 9.97. (340 aa)    
Predicted Functional Partners:
EKY29457.1
KEGG: cbe:Cbei_4324 0. DNA topoisomerase IV subunit B K02622; Psort location: Cytoplasmic, score: 9.67.
 
 0.994
EKY29459.1
KEGG: cbe:Cbei_4323 8.9e-192 DNA topoisomerase IV subunit A K02621; Psort location: Cytoplasmic, score: 9.97.
     0.993
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 0.980
EKY24034.1
S1 RNA binding domain protein.
  
  
 0.678
EKY29460.1
DJ-1 family protein; KEGG: gym:GYMC10_1577 4.6e-21 intracellular protease, PfpI family; K05520 protease I; Psort location: Cytoplasmic, score: 7.50.
     
 0.656
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 
 0.654
EKY22745.1
KEGG: cbe:Cbei_0830 6.8e-210 dnaK; molecular chaperone DnaK K04043; Psort location: Cytoplasmic, score: 9.97.
  
 
 
 0.652
EKY22744.1
Hypothetical protein; KEGG: cbe:Cbei_0830 8.2e-47 dnaK; molecular chaperone DnaK K04043; Psort location: Cytoplasmic, score: 9.97.
  
 
 
 0.622
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.597
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 
 0.543
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.