| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22237.1 | EKY26110.1 | HMPREF0216_03281 | HMPREF0216_02149 | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.551 |
| EKY22237.1 | EKY29377.1 | HMPREF0216_03281 | HMPREF0216_00238 | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | HAD hydrolase, family IB; KEGG: clj:CLJU_c09360 1.5e-61 phosphoserine phosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.851 |
| EKY22237.1 | EKY29378.1 | HMPREF0216_03281 | HMPREF0216_00239 | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | Aminotransferase, class IV; KEGG: cbt:CLH_0760 8.6e-68 enzyme of IlvE/PabC family; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 7.50. | 0.451 |
| EKY22237.1 | glyA | HMPREF0216_03281 | HMPREF0216_02267 | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.442 |
| EKY26110.1 | EKY22237.1 | HMPREF0216_02149 | HMPREF0216_03281 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Condensation domain protein; KEGG: ppy:PPE_00083 2.2e-20 bacitracin synthetase 3; Psort location: Cytoplasmic, score: 7.50. | 0.551 |
| EKY26110.1 | EKY29375.1 | HMPREF0216_02149 | HMPREF0216_00236 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbt:CLH_0758 5.8e-117 aspartate aminotransferase K00812. | 0.794 |
| EKY26110.1 | EKY29376.1 | HMPREF0216_02149 | HMPREF0216_00237 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: tte:TTE1368 1.2e-16 avtA3; aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 7.50. | 0.794 |
| EKY26110.1 | EKY29377.1 | HMPREF0216_02149 | HMPREF0216_00238 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | HAD hydrolase, family IB; KEGG: clj:CLJU_c09360 1.5e-61 phosphoserine phosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.833 |
| EKY26110.1 | EKY29378.1 | HMPREF0216_02149 | HMPREF0216_00239 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Aminotransferase, class IV; KEGG: cbt:CLH_0760 8.6e-68 enzyme of IlvE/PabC family; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 7.50. | 0.409 |
| EKY26110.1 | EKY29381.1 | HMPREF0216_02149 | HMPREF0216_00242 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Threonine synthase; KEGG: cbt:CLH_2639 3.8e-168 thrC; threonine synthase K01733. | 0.626 |
| EKY26110.1 | glyA | HMPREF0216_02149 | HMPREF0216_02267 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.878 |
| EKY26110.1 | hisF | HMPREF0216_02149 | HMPREF0216_02570 | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.402 |
| EKY29374.1 | EKY29375.1 | HMPREF0216_00235 | HMPREF0216_00236 | PHP domain protein; KEGG: dat:HRM2_10850 2.2e-37 two domain fusion protein includes: metal-dependent phosphoesterase / ribonuclease III; Psort location: Cytoplasmic, score: 7.50. | KEGG: cbt:CLH_0758 5.8e-117 aspartate aminotransferase K00812. | 0.788 |
| EKY29374.1 | EKY29376.1 | HMPREF0216_00235 | HMPREF0216_00237 | PHP domain protein; KEGG: dat:HRM2_10850 2.2e-37 two domain fusion protein includes: metal-dependent phosphoesterase / ribonuclease III; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: tte:TTE1368 1.2e-16 avtA3; aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 7.50. | 0.788 |
| EKY29374.1 | EKY29377.1 | HMPREF0216_00235 | HMPREF0216_00238 | PHP domain protein; KEGG: dat:HRM2_10850 2.2e-37 two domain fusion protein includes: metal-dependent phosphoesterase / ribonuclease III; Psort location: Cytoplasmic, score: 7.50. | HAD hydrolase, family IB; KEGG: clj:CLJU_c09360 1.5e-61 phosphoserine phosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.763 |
| EKY29374.1 | EKY29378.1 | HMPREF0216_00235 | HMPREF0216_00239 | PHP domain protein; KEGG: dat:HRM2_10850 2.2e-37 two domain fusion protein includes: metal-dependent phosphoesterase / ribonuclease III; Psort location: Cytoplasmic, score: 7.50. | Aminotransferase, class IV; KEGG: cbt:CLH_0760 8.6e-68 enzyme of IlvE/PabC family; K00826 branched-chain amino acid aminotransferase; Psort location: Cytoplasmic, score: 7.50. | 0.656 |
| EKY29375.1 | EKY26110.1 | HMPREF0216_00236 | HMPREF0216_02149 | KEGG: cbt:CLH_0758 5.8e-117 aspartate aminotransferase K00812. | KEGG: cbk:CLL_A2853 3.0e-271 5-methyltetrahydrofolate--homocysteine methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.794 |
| EKY29375.1 | EKY29374.1 | HMPREF0216_00236 | HMPREF0216_00235 | KEGG: cbt:CLH_0758 5.8e-117 aspartate aminotransferase K00812. | PHP domain protein; KEGG: dat:HRM2_10850 2.2e-37 two domain fusion protein includes: metal-dependent phosphoesterase / ribonuclease III; Psort location: Cytoplasmic, score: 7.50. | 0.788 |
| EKY29375.1 | EKY29376.1 | HMPREF0216_00236 | HMPREF0216_00237 | KEGG: cbt:CLH_0758 5.8e-117 aspartate aminotransferase K00812. | Hypothetical protein; KEGG: tte:TTE1368 1.2e-16 avtA3; aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 7.50. | 0.943 |
| EKY29375.1 | EKY29377.1 | HMPREF0216_00236 | HMPREF0216_00238 | KEGG: cbt:CLH_0758 5.8e-117 aspartate aminotransferase K00812. | HAD hydrolase, family IB; KEGG: clj:CLJU_c09360 1.5e-61 phosphoserine phosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.743 |
