| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY23257.1 | EKY25379.1 | HMPREF0216_03042 | HMPREF0216_02478 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | 0.829 |
| EKY23257.1 | EKY25396.1 | HMPREF0216_03042 | HMPREF0216_02495 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.829 |
| EKY23257.1 | EKY26296.1 | HMPREF0216_03042 | HMPREF0216_02078 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.811 |
| EKY23257.1 | EKY26446.1 | HMPREF0216_03042 | HMPREF0216_01942 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | FAD dependent oxidoreductase; KEGG: ctc:CTC00417 9.5e-101 oxidoreductase K00100; Psort location: Cytoplasmic, score: 7.50. | 0.751 |
| EKY23257.1 | EKY29328.1 | HMPREF0216_03042 | HMPREF0216_00296 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aminotransferase, class V; KEGG: cpr:CPR_0063 6.6e-148 aminotransferase, class V; K00839 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.878 |
| EKY23257.1 | EKY29329.1 | HMPREF0216_03042 | HMPREF0216_00297 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | KEGG: cbt:CLH_3217 2.5e-109 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.868 |
| EKY23257.1 | EKY29370.1 | HMPREF0216_03042 | HMPREF0216_00231 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; KEGG: cbk:CLL_A0790 9.0e-128 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.827 |
| EKY23257.1 | EKY29465.1 | HMPREF0216_03042 | HMPREF0216_00230 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pyruvate synthase; KEGG: cbt:CLH_0756 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.829 |
| EKY23257.1 | EKY29618.1 | HMPREF0216_03042 | HMPREF0216_00110 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | NAD-dependent malic enzyme; KEGG: cbe:Cbei_5075 2.9e-163 malate dehydrogenase. | 0.787 |
| EKY23257.1 | glyA | HMPREF0216_03042 | HMPREF0216_02267 | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.813 |
| EKY25379.1 | EKY23257.1 | HMPREF0216_02478 | HMPREF0216_03042 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Aminotransferase, class III; KEGG: gym:GYMC10_0624 8.6e-123 aminotransferase class-III; K07250 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.829 |
| EKY25379.1 | EKY25396.1 | HMPREF0216_02478 | HMPREF0216_02495 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Pyruvate synthase; KEGG: cbt:CLH_2077 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.999 |
| EKY25379.1 | EKY26296.1 | HMPREF0216_02478 | HMPREF0216_02078 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Putative glycerate dehydrogenase; KEGG: cbk:CLL_A0984 3.9e-111 2-hydroxyacid dehydrogenase; Psort location: Cytoplasmic, score: 9.67; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.893 |
| EKY25379.1 | EKY26446.1 | HMPREF0216_02478 | HMPREF0216_01942 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | FAD dependent oxidoreductase; KEGG: ctc:CTC00417 9.5e-101 oxidoreductase K00100; Psort location: Cytoplasmic, score: 7.50. | 0.933 |
| EKY25379.1 | EKY29328.1 | HMPREF0216_02478 | HMPREF0216_00296 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Aminotransferase, class V; KEGG: cpr:CPR_0063 6.6e-148 aminotransferase, class V; K00839 aminotransferase; Psort location: Cytoplasmic, score: 9.97. | 0.862 |
| EKY25379.1 | EKY29329.1 | HMPREF0216_02478 | HMPREF0216_00297 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | KEGG: cbt:CLH_3217 2.5e-109 D-3-phosphoglycerate dehydrogenase K00058; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.885 |
| EKY25379.1 | EKY29370.1 | HMPREF0216_02478 | HMPREF0216_00231 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Hypothetical protein; KEGG: cbk:CLL_A0790 9.0e-128 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737. | 0.999 |
| EKY25379.1 | EKY29465.1 | HMPREF0216_02478 | HMPREF0216_00230 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Pyruvate synthase; KEGG: cbt:CLH_0756 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| EKY25379.1 | EKY29618.1 | HMPREF0216_02478 | HMPREF0216_00110 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | NAD-dependent malic enzyme; KEGG: cbe:Cbei_5075 2.9e-163 malate dehydrogenase. | 0.895 |
| EKY25379.1 | glyA | HMPREF0216_02478 | HMPREF0216_02267 | Pyruvate synthase; KEGG: cdc:CD196_2523 0. nifJ; pyruvate-flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.525 |