| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22075.1 | EKY28348.1 | HMPREF0216_03405 | HMPREF0216_00870 | Methyltransferase domain protein; KEGG: mma:MM_1949 1.4e-17 methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50. | Putative chlorohydrolase/aminohydrolase; KEGG: ssm:Spirs_1387 1.0e-64 selenium metabolism protein SsnA; Psort location: Cytoplasmic, score: 7.50. | 0.553 |
| EKY22075.1 | EKY28812.1 | HMPREF0216_03405 | HMPREF0216_00556 | Methyltransferase domain protein; KEGG: mma:MM_1949 1.4e-17 methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.553 |
| EKY22075.1 | EKY29331.1 | HMPREF0216_03405 | HMPREF0216_00299 | Methyltransferase domain protein; KEGG: mma:MM_1949 1.4e-17 methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.802 |
| EKY22075.1 | luxS | HMPREF0216_03405 | HMPREF0216_02147 | Methyltransferase domain protein; KEGG: mma:MM_1949 1.4e-17 methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.576 |
| EKY26657.1 | EKY26966.1 | HMPREF0216_01842 | HMPREF0216_01569 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Pyridoxal phosphate enzyme, YggS family; KEGG: ddd:Dda3937_02601 2.1e-25 yggS; putative enzyme K06997; Psort location: Cytoplasmic, score: 7.50; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.778 |
| EKY26657.1 | EKY27256.1 | HMPREF0216_01842 | HMPREF0216_01508 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.800 |
| EKY26657.1 | EKY28348.1 | HMPREF0216_01842 | HMPREF0216_00870 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Putative chlorohydrolase/aminohydrolase; KEGG: ssm:Spirs_1387 1.0e-64 selenium metabolism protein SsnA; Psort location: Cytoplasmic, score: 7.50. | 0.793 |
| EKY26657.1 | EKY28437.1 | HMPREF0216_01842 | HMPREF0216_00788 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Haloacid dehalogenase-like hydrolase. | 0.762 |
| EKY26657.1 | EKY28812.1 | HMPREF0216_01842 | HMPREF0216_00556 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.793 |
| EKY26657.1 | EKY29331.1 | HMPREF0216_01842 | HMPREF0216_00299 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.795 |
| EKY26657.1 | luxS | HMPREF0216_01842 | HMPREF0216_02147 | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.418 |
| EKY26966.1 | EKY26657.1 | HMPREF0216_01569 | HMPREF0216_01842 | Pyridoxal phosphate enzyme, YggS family; KEGG: ddd:Dda3937_02601 2.1e-25 yggS; putative enzyme K06997; Psort location: Cytoplasmic, score: 7.50; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.778 |
| EKY26966.1 | EKY28426.1 | HMPREF0216_01569 | HMPREF0216_00777 | Pyridoxal phosphate enzyme, YggS family; KEGG: ddd:Dda3937_02601 2.1e-25 yggS; putative enzyme K06997; Psort location: Cytoplasmic, score: 7.50; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Class II glutamine amidotransferase. | 0.424 |
| EKY26966.1 | EKY29331.1 | HMPREF0216_01569 | HMPREF0216_00299 | Pyridoxal phosphate enzyme, YggS family; KEGG: ddd:Dda3937_02601 2.1e-25 yggS; putative enzyme K06997; Psort location: Cytoplasmic, score: 7.50; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.672 |
| EKY27256.1 | EKY26657.1 | HMPREF0216_01508 | HMPREF0216_01842 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.800 |
| EKY27256.1 | EKY28348.1 | HMPREF0216_01508 | HMPREF0216_00870 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative chlorohydrolase/aminohydrolase; KEGG: ssm:Spirs_1387 1.0e-64 selenium metabolism protein SsnA; Psort location: Cytoplasmic, score: 7.50. | 0.795 |
| EKY27256.1 | EKY28812.1 | HMPREF0216_01508 | HMPREF0216_00556 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.908 |
| EKY27256.1 | EKY29331.1 | HMPREF0216_01508 | HMPREF0216_00299 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.799 |
| EKY28348.1 | EKY22075.1 | HMPREF0216_00870 | HMPREF0216_03405 | Putative chlorohydrolase/aminohydrolase; KEGG: ssm:Spirs_1387 1.0e-64 selenium metabolism protein SsnA; Psort location: Cytoplasmic, score: 7.50. | Methyltransferase domain protein; KEGG: mma:MM_1949 1.4e-17 methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50. | 0.553 |
| EKY28348.1 | EKY26657.1 | HMPREF0216_00870 | HMPREF0216_01842 | Putative chlorohydrolase/aminohydrolase; KEGG: ssm:Spirs_1387 1.0e-64 selenium metabolism protein SsnA; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.793 |