| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY22120.1 | EKY22779.1 | HMPREF0216_03450 | HMPREF0216_03143 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 0.793 |
| EKY22120.1 | argG | HMPREF0216_03450 | HMPREF0216_01041 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.866 |
| EKY22120.1 | asd | HMPREF0216_03450 | HMPREF0216_02751 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.986 |
| EKY22120.1 | dapA | HMPREF0216_03450 | HMPREF0216_02750 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.781 |
| EKY22120.1 | dapB | HMPREF0216_03450 | HMPREF0216_02749 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.717 |
| EKY22120.1 | dapF | HMPREF0216_03450 | HMPREF0216_01578 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.797 |
| EKY22120.1 | dapH | HMPREF0216_03450 | HMPREF0216_02741 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.619 |
| EKY22120.1 | lysA | HMPREF0216_03450 | HMPREF0216_00461 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.883 |
| EKY22120.1 | murE | HMPREF0216_03450 | HMPREF0216_01561 | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.416 |
| EKY22779.1 | EKY22120.1 | HMPREF0216_03143 | HMPREF0216_03450 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Aspartate kinase I; KEGG: cbk:CLL_A1282 1.2e-134 aspartate kinase I K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 0.793 |
| EKY22779.1 | argG | HMPREF0216_03143 | HMPREF0216_01041 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.872 |
| EKY22779.1 | asd | HMPREF0216_03143 | HMPREF0216_02751 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.983 |
| EKY22779.1 | dapA | HMPREF0216_03143 | HMPREF0216_02750 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.644 |
| EKY22779.1 | dapB | HMPREF0216_03143 | HMPREF0216_02749 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.623 |
| EKY22779.1 | dapF | HMPREF0216_03143 | HMPREF0216_01578 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.648 |
| EKY22779.1 | dapH | HMPREF0216_03143 | HMPREF0216_02741 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.668 |
| EKY22779.1 | lysA | HMPREF0216_03143 | HMPREF0216_00461 | Aspartate kinase; KEGG: cbk:CLL_A1047 2.9e-170 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.939 |
| EKY25313.1 | dapF | HMPREF0216_02536 | HMPREF0216_01578 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.816 |
| EKY25313.1 | lysA | HMPREF0216_02536 | HMPREF0216_00461 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.924 |
| EKY25313.1 | murE | HMPREF0216_02536 | HMPREF0216_01561 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.795 |