STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBPutative NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (245 aa)    
Predicted Functional Partners:
EKY29456.1
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: cbk:CLL_A0779 2.7e-190 gluD; glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.986
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.912
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.879
EKY25398.1
Hypothetical protein; KEGG: clo:HMPREF0868_0202 3.2e-22 isochorismatase family protein; Psort location: Cytoplasmic, score: 7.50.
  
 0.861
EKY25416.1
Hydrolase, NUDIX family; KEGG: clj:CLJU_c19510 2.0e-59 putative pyrophosphohydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50.
  
 
  0.857
deoD
KEGG: cno:NT01CX_2329 4.4e-80 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.67.
    
 0.855
nadK
Inorganic polyphosphate/ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.851
EKY27256.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.831
EKY28449.1
KEGG: cpr:CPR_1971 1.3e-112 IunH family nucleoside hydrolase; K01239 purine nucleosidase; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.825
EKY27241.1
MazG family protein; KEGG: bmd:BMD_0076 1.2e-102 tetrapyrrole methylase family protein / MazG family protein K02499; Psort location: Cytoplasmic, score: 7.50.
    
  0.737
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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