| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EKY26139.1 | EKY27532.1 | HMPREF0216_02178 | HMPREF0216_01342 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | 0.675 |
| EKY26139.1 | EKY27727.1 | HMPREF0216_02178 | HMPREF0216_01201 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Pyruvate kinase; KEGG: cbe:Cbei_4851 1.2e-187 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 0.833 |
| EKY26139.1 | EKY28158.1 | HMPREF0216_02178 | HMPREF0216_01001 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Phosphoglycerate kinase. | 0.793 |
| EKY26139.1 | EKY28159.1 | HMPREF0216_02178 | HMPREF0216_01002 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Hypothetical protein; Belongs to the phosphoglycerate kinase family. | 0.716 |
| EKY26139.1 | EKY28160.1 | HMPREF0216_02178 | HMPREF0216_01003 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.886 |
| EKY26139.1 | EKY28731.1 | HMPREF0216_02178 | HMPREF0216_00579 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Class II aldolase, tagatose bisphosphate family; KEGG: cdf:CD3074 1.3e-117 gatY; tagatose-bisphosphate aldolase K08302; Psort location: Cytoplasmic, score: 7.50. | 0.916 |
| EKY26139.1 | pfkA | HMPREF0216_02178 | HMPREF0216_01202 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.982 |
| EKY26139.1 | pfp | HMPREF0216_02178 | HMPREF0216_01461 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.979 |
| EKY26139.1 | pgi | HMPREF0216_02178 | HMPREF0216_03259 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | KEGG: cbk:CLL_A0403 4.0e-196 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family. | 0.997 |
| EKY26139.1 | tpiA | HMPREF0216_02178 | HMPREF0216_01000 | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.843 |
| EKY27532.1 | EKY26139.1 | HMPREF0216_01342 | HMPREF0216_02178 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Pyruvate kinase, barrel domain protein; KEGG: cbe:Cbei_1412 4.3e-73 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 0.675 |
| EKY27532.1 | EKY27727.1 | HMPREF0216_01342 | HMPREF0216_01201 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Pyruvate kinase; KEGG: cbe:Cbei_4851 1.2e-187 pyruvate kinase K00873; Belongs to the pyruvate kinase family. | 0.675 |
| EKY27532.1 | EKY28158.1 | HMPREF0216_01342 | HMPREF0216_01001 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Phosphoglycerate kinase. | 0.613 |
| EKY27532.1 | EKY28159.1 | HMPREF0216_01342 | HMPREF0216_01002 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; Belongs to the phosphoglycerate kinase family. | 0.613 |
| EKY27532.1 | EKY28160.1 | HMPREF0216_01342 | HMPREF0216_01003 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.626 |
| EKY27532.1 | EKY28731.1 | HMPREF0216_01342 | HMPREF0216_00579 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Class II aldolase, tagatose bisphosphate family; KEGG: cdf:CD3074 1.3e-117 gatY; tagatose-bisphosphate aldolase K08302; Psort location: Cytoplasmic, score: 7.50. | 0.960 |
| EKY27532.1 | pfkA | HMPREF0216_01342 | HMPREF0216_01202 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.584 |
| EKY27532.1 | pfp | HMPREF0216_01342 | HMPREF0216_01461 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.584 |
| EKY27532.1 | pgi | HMPREF0216_01342 | HMPREF0216_03259 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: cbk:CLL_A0403 4.0e-196 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family. | 0.822 |
| EKY27532.1 | tpiA | HMPREF0216_01342 | HMPREF0216_01000 | PTS system fructose-specific EIIABC component; KEGG: cbe:Cbei_1844 2.2e-234 PTS system, fructose subfamily, IIC subunit; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.685 |