Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EKY28530.1KEGG: snc:HMPREF0837_11560 6.8e-12 CAAX amino terminal protease family protein; Psort location: CytoplasmicMembrane, score: 10.00. (289 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.468
EKY29649.1
Hypothetical protein; KEGG: tpr:Tpau_4044 1.8e-18 queuine tRNA-ribosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.454
EKY28529.1
Hypothetical protein; Belongs to the UPF0145 family.
       0.447
EKY28528.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.430
EKY26721.1
Hypothetical protein; KEGG: edi:EDI_341030 1.2e-08 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 7.50.
  
     0.428
EKY29692.1
ABC-2 type transporter; Psort location: CytoplasmicMembrane, score: 9.35.
   
  
 0.409
EKY29693.1
ABC-2 type transporter; KEGG: phu:Phum_PHUM026790 0.00021 ABC transporter, putative; Psort location: CytoplasmicMembrane, score: 10.00.
   
  
 0.409
EKY27331.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
    0.404
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
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