Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKY28412.1Cof-like hydrolase. (286 aa)    
Predicted Functional Partners:
EKY28433.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.810
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.617
EKY28194.1
Phosphoribulokinase/uridine kinase family protein.
   
 
  0.585
EKY29652.1
KEGG: bmq:BMQ_3353 6.3e-207 PTS system, beta-glucoside-specific IIABC component; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.582
EKY28978.1
PTS system, beta-glucoside-specific, IIABC component.
    
 0.582
EKY28434.1
Riboflavin synthase, alpha subunit.
     
 0.551
EKY24021.1
Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.519
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.514
EKY22114.1
Riboflavin kinase; KEGG: cbk:CLL_A1277 2.4e-40 ribF; bifunctional riboflavin kinase/FMN adenylyltransferase K11753.
    
 0.503
EKY22115.1
Putative riboflavin biosynthesis protein RibF; KEGG: cpf:CPF_1936 2.4e-47 ribF, ribC; bifunctional riboflavin kinase/FMN adenylyltransferase K11753.
    
 0.503
Your Current Organism:
Clostridium celatum
NCBI taxonomy Id: 545697
Other names: C. celatum DSM 1785, Clostridium celatum DSM 1785
Server load: medium (50%) [HD]